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American Journal of Medical Quality
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Article

Glycemic Control and Insulin Safety: The Impact of Computerized Intravenous Insulin Dosing

Samuel J. Flanders, MD1*, Rattan Juneja, MBBS, MD, MRCP2, Corbin P. Roudebush, MD3, Joni Carroll, RN, CDE4, Adam Golas, MPH3, and Beth L. Elias, PhD5

1 Beaumont Hospitals, Royal Oak, Michigan
2 Indiana University School of Medicine, Indianapolis, Indiana; Clarian Health, Indianapolis, Indiana
3 Indiana University School of Medicine, Indianapolis, Indiana
4 Indiana University Hospital, Indianapolis, Indiana; Clarian Health, Indianapolis, Indiana
5 University of Alabama School of Nursing, Birmingham

* To whom correspondence should be addressed. E-mail: Samuel.flanders{at}beaumont.org.


   Abstract
The aim of this work was to evaluate our Glycemic Control Initiative that was put in place to improve blood glucose control in hyperglycemic intensive care patients and improve insulin safety by minimizing the risk of hypoglycemia. A computerized decision-support tool was developed for intravenous insulin dosing that provided an automated and standardized approach across the organization’s intensive care units (ICUs). As a result of this, at 3 years post implementation, ICU patients are 2.28 times more likely to have blood glucose levels <150 mg/dL (odds ratio = 2.28; 95% confidence interval = 2.25-2.30; P < .001) compared with the baseline period. Although glycemic control was significantly improved, the patient safety risk from hypoglycemia did not increase, as rates of blood glucose <50 mg/dL decreased from 0.68% at baseline to 0.64% in 2007. (Am J Med Qual XXXX;XX:xx-xx)

First published on August 7, 2009, doi:10.1177/1062860609338406

American Journal of Medical Quality 2009;24:489.

A more recent version of this article appeared on November 1, 2009


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